ANI
New Delhi: Recent study published on SpringerLink sheds light on potential side effects of Covaxin, particularly among female adolescents with a history of allergies. This comes after weeks of controversy surrounding the AstraZeneca vaccine, Covishield.
The observational study, led by Dr. Sankha Shubhra Chakrabarti and researchers at Banaras Hindu University, focused on 1,024 participants. While only 635 adolescents and 291 adults were followed up with for a year, the findings revealed a higher risk of Adverse Events of Special Interest (AESI) in female adolescents who had pre-existing allergies.
The study identified various AESI categories in participants who received Covaxin:
Serious but rare cases of Guillain-Barre Syndrome (0.3%) and stroke (1%) were also reported.
Adults with existing health conditions (comorbidities) were twice as likely to experience persistent AESI. Notably, adults with hypertension faced a higher risk of AESI after vaccination compared to those without.
AESI is a designated term encompassing specific adverse events identified before the rollout of COVID-19 vaccines. It includes conditions like thrombosis with thrombocytopenia syndrome (TTS), myocarditis, blood clots, low platelet levels, and anaphylaxis.
The study highlights the importance of recognizing potential differences in adverse event patterns between adults and adolescents. This knowledge can help guide future vaccination strategies and post-vaccination monitoring.
The study involved a follow-up with only a portion of the initial participants. Further research with larger cohorts might be required for more conclusive results.
The findings of this study emphasize the need for continued vigilance regarding potential side effects associated with COVID-19 vaccines. By understanding these risks, particularly in vulnerable populations, appropriate measures can be taken to ensure vaccine safety and effectiveness.
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