After Covishield, now reports says even Covaxin might lead you to death

The findings revealed a higher risk of Adverse Events of Special Interest (AESI) in female adolescents who had pre-existing allergies.

Mayank Kasyap
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Courtesy: ANI

New Delhi: Recent study published on SpringerLink sheds light on potential side effects of Covaxin, particularly among female adolescents with a history of allergies. This comes after weeks of controversy surrounding the AstraZeneca vaccine, Covishield.

Higher risk for female adolescents with allergies

The observational study, led by Dr. Sankha Shubhra Chakrabarti and researchers at Banaras Hindu University, focused on 1,024 participants. While only 635 adolescents and 291 adults were followed up with for a year, the findings revealed a higher risk of Adverse Events of Special Interest (AESI) in female adolescents who had pre-existing allergies.

Types of reported AESI

The study identified various AESI categories in participants who received Covaxin:

  • General Disorders: 10.2%
  • New-onset Skin & Subcutaneous Disorders: 10.5%
  • Musculoskeletal Disorders: 5.8%
  • Nervous System Disorders: 5.5%
  • Menstrual Abnormalities (females only): 4.6%

Serious but rare cases of Guillain-Barre Syndrome (0.3%) and stroke (1%) were also reported.

Comorbidities and persistent AESI

Adults with existing health conditions (comorbidities) were twice as likely to experience persistent AESI. Notably, adults with hypertension faced a higher risk of AESI after vaccination compared to those without.

Importance of understanding AESI

AESI is a designated term encompassing specific adverse events identified before the rollout of COVID-19 vaccines. It includes conditions like thrombosis with thrombocytopenia syndrome (TTS), myocarditis, blood clots, low platelet levels, and anaphylaxis.

Understanding patterns for different age groups

The study highlights the importance of recognizing potential differences in adverse event patterns between adults and adolescents. This knowledge can help guide future vaccination strategies and post-vaccination monitoring.

Limitations to consider

The study involved a follow-up with only a portion of the initial participants. Further research with larger cohorts might be required for more conclusive results.

Need to be vigilant regarding vaccine side effects 

The findings of this study emphasize the need for continued vigilance regarding potential side effects associated with COVID-19 vaccines. By understanding these risks, particularly in vulnerable populations, appropriate measures can be taken to ensure vaccine safety and effectiveness.